L-alpha-Dipalmitoyl phosphatidylcholine
L-alpha-Dipalmitoyl phosphatidylcholine
CAS: 63-89-8
Molecular Formula: C40H80NO8P
L-alpha-Dipalmitoyl phosphatidylcholine - Names and Identifiers
| Name | L-alpha-Dipalmitoyl phosphatidylcholine |
| Synonyms | colfosceril palmitate L-a-Lecitin-dipalmitoyl L-a-Dipalmitoyl Lecithin L-A-LECITHIN DIPALMITOYL L-alpha-Dipalmitoyl phosphatidylcholine 1,2-dipalmitoyl-3-sn-phosphatidylcholine 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine 1,2-dipalmitoyl-L-alpha-phosphatidylcholine L-A-phosphatidylcholine dipalmitoyl*synthetic 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine monohydrate (R)-2,3-Bis(palMitoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate |
| CAS | 63-89-8 |
| EINECS | 200-567-6 |
| InChI | InChI=1/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1 |
| InChIKey | KILNVBDSWZSGLL-KXQOOQHDSA-N |
L-alpha-Dipalmitoyl phosphatidylcholine - Physico-chemical Properties
| Molecular Formula | C40H80NO8P |
| Molar Mass | 734.04 |
| Melting Point | 229-229.5 °C |
| Boling Point | 229-229.5℃ |
| Specific Rotation(α) | D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Form Solid, color White to Off-White |
| Color | White to Off-White |
| Merck | 14,2477 |
| Storage Condition | -20°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Physical and Chemical Properties | Chemical properties Monohydrate: Crystallization from thermal diisobutanone. Softened at 75~79 ℃. [α]D23 6.6. (C = 4.2,1:1 chloroform-methanol). Easily soluble in chloroform, hot diisobutanone or hot dioxane. Easily emulsified in water. Solubility at 22-23 ℃ (g/100ml): ethanol 1.5, ether 0.02, acetone 0.02, pyridine 1.1, acetic acid 4.0, methanol 1.4. |
| Use | The application is natural surface active substance, which is the main component of exogenous surface active substance preparation. It is used to rescue newborns with a birth weight of 700g or more who are mechanically ventilated for RDS. |
L-alpha-Dipalmitoyl phosphatidylcholine - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29232000 |
L-alpha-Dipalmitoyl phosphatidylcholine - Upstream Downstream Industry
L-alpha-Dipalmitoyl phosphatidylcholine - Reference
| Reference Show more | 1. [IF=6.953] Jun Meng et al."Coating function and stabilizing effects of surface layer protein from Lactobacillus acidophilus ATCC 4356 on liposomes."Int J Biol Macromol. 2021 Jul;183:457 2. [IF=6.057] Qian Liu et al."A novel electrochemical aptasensor for exosomes determination and release based on specific host-guest interactions between cucurbit [7]uril and ferrocene."Talanta. 2021 Sep;232:122451 |
L-alpha-Dipalmitoyl phosphatidylcholine - Nature
| specific rotation | D23 6.6° (c = 4.2 in 1:1 chloroform-methanol) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
Last Update：2024-04-10 22:29:15
L-alpha-Dipalmitoyl phosphatidylcholine - Uses and synthesis methods
biological activity
DPPC (129Y83) is a phosphoglyceride that can be used to prepare liposome monolayers. DPPC-liposome can be effectively used as a delivery vehicle for the induction of immune responses against GSL antigens in mice.
Target
Human Endogenous Metabolite
Production method
Synthetic surfactant, composed of palmitchphos plus decane alcohol and telosapor (Tyloxapo1).
Last Update：2024-04-09 21:21:28
L-alpha-Dipalmitoyl phosphatidylcholine - Reference Information
| biological activity | DPPC (129Y83) is a phosphoglyceride that can be used to prepare liposomes Monolayer. DPPC-liposome can be effectively used as a delivery vehicle for the induction of immune responses against GSL antigens in mice. |
| target | Human Endogenous Metabolite |
| chemical properties | monohydrate: crystallized from hot diisobutanone. Softened at 75~79 ℃. [α]D23 6.6. (C = 4.2,1:1 chloroform-methanol). Easily soluble in chloroform, hot diisobutanone or hot dioxane. Easily emulsified in water. Solubility at 22-23 ℃ (g/100ml): ethanol 1.5, ether 0.02, acetone 0.02, pyridine 1.1, acetic acid 4.0, methanol 1.4. |
| use | is a natural surface active substance and is the main component of exogenous surface active substance preparation. It is used to rescue newborns with a birth weight of 700g or more who are mechanically ventilated for RDS. |
| production method | synthetic surfactant, composed of palmnchphos plus decadecyl alcohol and Tyrosapor (Tyloxapo1) composition. |
Last Update：2024-04-09 21:11:58
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Spot supply
Product Name: Lecithin Impurity 21 Visit Supplier Webpage Request for quotationCAS: 63-89-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Dipalmitoyl Phosphatidylcholine Visit Supplier Webpage Request for quotationCAS: 63-89-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for L-alpha-Dipalmitoyl phosphatidylcholine
TYLOXAPOL
[S,(+)]-1-O,2-O-Dipalmitoyl-3-O-trityl-L-glycerol
2-CHLOROETHYLPHOSPHORIC ACID DICHLORIDE
Choline glycerophosphate
Choline tosylate
Palmitic acid
[S,(+)]-1-O,2-O-Dipalmitoyl-3-O-trityl-L-glycerol
2-CHLOROETHYLPHOSPHORIC ACID DICHLORIDE
Choline glycerophosphate
Choline tosylate
Palmitic acid